Fermentation Filtration

Complete sterility with unrivalled contaminant control.

Overview

Prevent contamination at all costs. As the fermentation process becomes more complex, the potential risk for contamination ingress has never been higher.

Filtration plays a key role alongside basic aseptic design, sterilisation and sanitisation regimes. So, whether your fermentation process uses small bioreactors or large industrial scale fermenters, we'll help you reduce contamination while maximising your productivity.

control-ph-contamination

Control pH contamination

Strong acids and bases have been shown to support microbial contaminants. Fermenter additions such as phosphoric acid can harbour spores that proliferate quickly inside a fermenter. We provide compatible sterilising grade filtration to eliminate this problem.

challenge-of-sterilising-antifoam

Tackle the challenge of sterilising antifoam

Heat sterilisation of antifoams is common but causes problems. The viscous nature of antifoams such as PPG and the dry heat process means that complete sterilisation is often not achieved. High temperatures also lead to degradation of the antifoam and lower efficacy. Our sterile filtration solutions are a viable alternative to ensure sterilisation without compromise.

optimise-fermentation-without-the-cost

Optimise your fermentation process without the cost

The desire to maximise yields and shorten fermentation times often leads to the gradual increase of VVM to each fermenter. This can lead to air starvation and the possibility of having to invest in new compressors. To mitigate this, we replace existing pre and sterile inlet air filters to significantly reduce the differential pressure and free up capacity in your compressed air generation.

Get industry-leading fermentation control

We're Europe's leading developer of bespoke fermentation filtration solutions. We can work with your pre-existing cartridges or housings from all major manufacturers giving you complete flexibility. Whatever your needs, Amazon Filters is here for you.

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Our Filtration Solutions

supaporepp SupaPore PPG

Working as both a membrane pre-filter and a final polishing filter, SupaPore PPG suits a wide range of liquid processes. Thermal welding replaces adhesives throughout, keeping extractables out of the filtrate.

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supaporevpbev SupaPore FPG

Graded-density glass microfibre media loads dirt through its full depth, at an absolute rating. It clarifies beverages, fine chemicals, and treated water.

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supaporevp SupaPore VP

A pleated, high-surface-area PES membrane for a wide range of liquid processing. Naturally hydrophilic, it contains no wetting agents and holds very low extractables for clean, consistent filtrate.

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Supa-Pore-Group-2-cut-out-e1519301886448 SupaPore VPBA

Pairs a high-flow, asymmetric PES membrane with a built-in pre-filter layer, improving steam life and dirt-holding on heavily loaded pharmaceutical solutions. The second layer also wets more evenly for integrity testing.

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Capsule filters from Amazon Filters SupaPore THB

An expanded PTFE membrane over a large-bore core pushes high air and gas flow at low pressure drop, for fermenter off-gas, inlet air, and CO₂ lines. It won't wet out with water vapour, and steam-sterilises repeatedly.

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SupaPore TMB SupaPore TMB

Heat-resistant supports and hardware enable our SupaPore hydrophobic PTFE membrane to vent continuously at up to 90 °C. It keeps WFI tanks and fermenter inlet air sterile where the vent runs hot continuously, not just during sterilisation.

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SupaPore VPH SupaPore VPH

Particularly suited to purified water systems, this pleated, high-surface-area PES membrane holds no wetting agents and very low extractables. It stands up to repeated steaming, autoclaving, and hot-water sanitisation.

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71 series sanitary housings from Amazon Filters 71 Series

Hygienic tank vent housings with one combined inlet and outlet connection, mounting straight onto a sealed storage vessel. The seal-less Vee clamp releases by hand.

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72C series ASME BPE sanitary housings from Amazon Filters 72C Series ASME BPE

ASME BPE conforming housings that drain completely in the vertical position, for aseptic biopharmaceutical processing. Nothing collects in the base between batches.

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72C series in-line ASME BPE sanitary housings from Amazon Filters 72C Series In-Line ASME BPE

In-line housings with ASME BPE Tri-Clamp ferrules at 1, 1½, and 2 inches. They drop into existing pipework without a base mount and take up no floor space.

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74 series sanitary housings from Amazon Filters 74A Series

Plenum style housings for in-line mounting, taking elements up to 30 inches in gas and liquid processes. On gas lines, condensate drains away below the cartridge chamber.

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76B series sanitary housings from Amazon Filters 76B Series

Crevice-free housings with a 0.4 µm Ra internal finish, in 316L or Alloy 22. The self-draining base cuts pressure loss, and they sanitise or steam sterilise in place.

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76C series ASME BPE sanitary housings from Amazon Filters 76C Series ASME BPE

Housings configured for low pressure drop in high flow gas, conforming to ASME BPE. Body lengths cover 5 to 30 inch cartridges, with Tri-Clamp ferrules at 1 and 1½ inches.

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Heating jackets for 50 & 70 series housings from Amazon Filters Heating Jackets for 50 & 70 Series Housings

Silicone or stainless steel jackets that wrap around 50 and 70 Series housings to stabilise temperature and prevent condensation on vent filters. Stainless steel carries an ATEX zone 1 and 2 rating.

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Certification & Approvals

All our products are manufactured in accordance with Quality Standard ISO 9001, Environment Standard ISO 14001 and Health & Safety Standard ISO 45001.

We are committed to manufacturing quality filtration solutions and adhere to the requirements of:

USP_04.17 ASME 1 European Regulation (EC) Number 1935-2004-1 FDA PED 2 PESR atex-certification-services-1

Let’s get started

Zero annual contaminations and maximised productivity are within your reach.